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Agile BioScience: Probing Protein Stability with DSC
Differential Scanning Calorimetry (DSC) is a powerful technique for understanding the thermal stability and unfolding behavior of biopharmaceuticals. Agile BioScience employs DSC to support your development process, ensuring optimal product quality and efficacy.
Why DSC Matters:
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Reveals Unfolding Transitions: DSC measures the heat absorbed or released during protein unfolding, providing insights into conformational stability.
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Determines Melting Temperature (Tm): Identifies the temperature at which a protein begins to denature, a critical parameter for storage and formulation.
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Assesses Manufacturing Impact: Compares batches and investigates how process changes might affect protein stability.
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Supports Regulatory Submissions: Provides data relevant to product quality and stability assessments.
Our Approach:
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High-Sensitivity Instrumentation: Our DSC systems deliver accurate and precise measurements of thermal transitions.
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Tailored Method Development: We carefully optimize experimental conditions to match your specific biopharmaceutical.
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Expert Data Interpretation: Our team translates DSC data into actionable insights about your protein's stability profile.
Benefits of Choosing Agile BioScience:
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Confidence in Stability: Gain a deep understanding of your protein's thermal behavior.
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Formulation Optimization: Identify conditions that maximize stability and shelf-life.
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Data-Driven Decision Making: Make informed decisions about manufacturing, storage, and product development.
Contact us to learn how DSC can ensure the stability and quality of your biopharmaceuticals.
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Differential Scanning Calorimetry (DSC)