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Agile BioScience: Probing Protein Stability with DSC

Differential Scanning Calorimetry (DSC) is a powerful technique for understanding the thermal stability and unfolding behavior of biopharmaceuticals. Agile BioScience employs DSC to support your development process, ensuring optimal product quality and efficacy.

Why DSC Matters:

  • Reveals Unfolding Transitions: DSC measures the heat absorbed or released during protein unfolding, providing insights into conformational stability.

  • Determines Melting Temperature (Tm): Identifies the temperature at which a protein begins to denature, a critical parameter for storage and formulation.

  • Assesses Manufacturing Impact: Compares batches and investigates how process changes might affect protein stability.

  • Supports Regulatory Submissions: Provides data relevant to product quality and stability assessments.

Our Approach:

  • High-Sensitivity Instrumentation: Our DSC systems deliver accurate and precise measurements of thermal transitions.

  • Tailored Method Development: We carefully optimize experimental conditions to match your specific biopharmaceutical.

  • Expert Data Interpretation: Our team translates DSC data into actionable insights about your protein's stability profile.

Benefits of Choosing Agile BioScience:

  • Confidence in Stability: Gain a deep understanding of your protein's thermal behavior.

  • Formulation Optimization: Identify conditions that maximize stability and shelf-life.

  • Data-Driven Decision Making: Make informed decisions about manufacturing, storage, and product development.

Contact us to learn how DSC can ensure the stability and quality of your biopharmaceuticals.

Differential Scanning Calorimetry (DSC)

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Agile BioScience: High-Performance Analysis with Liquid Chromatography

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